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Dexpramipexole dihydrochloride
CAS No. 104632-27-1
Dexpramipexole dihydrochloride ( R)-Pramipexole;KNS-760704 )
产品货号. M10229 CAS No. 104632-27-1
A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥356 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
|
| 25MG | ￥1256 | 有现货 |
|
| 50MG | ￥2130 | 有现货 |
|
| 100MG | ￥3216 | 有现货 |
|
| 200MG | ￥4714 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Dexpramipexole dihydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
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产品描述A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively; also possesses low/insignificant affinity (500–10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors; used for treating Parkinson's disease (PD) and restless legs syndrome (RLS).Alzheimer's Disease Phase 2 Clinical
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同义词R)-Pramipexole;KNS-760704
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体Dopamine Receptor
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研究领域Neurological Disease
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适应症Alzheimer Disease
化学信息
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CAS Number104632-27-1
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分子量284.25
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分子式C10H19Cl2N3S
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 28 mg/mL
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SMILESCCCNC1CCC2=C(C1)SC(=N2)N.Cl.Cl
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化学全称2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6R)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Alavian KN, et al. Brain Res. 2012 Mar 29;1446:1-11.
2. Cudkowicz M, et al. Nat Med. 2011 Nov 20;17(12):1652-6.
3. Bozik ME, et al. J Clin Pharmacol. 2011 Aug;51(8):1177-85.
2. Cudkowicz M, et al. Nat Med. 2011 Nov 20;17(12):1652-6.
3. Bozik ME, et al. J Clin Pharmacol. 2011 Aug;51(8):1177-85.
产品手册
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